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Cartilage is the type of tough connective tissue with a flexible matrix made of collagen, protein and sugars which covers the ends of your bones at a joint. It also gives shape and support to other parts of your body, such as your ears, nose and windpipe. Healthy cartilage helps you move by allowing your bones to glide over each other. It also protects bones by preventing them from rubbing against each other (1).
A disorder which depletes the cartilage and weakens the joint is called as Osteoarthritis (OA). It also known as degenerative arthritis, degenerative joint disease or osteoarthritis, is a type of joint disease that results from breakdown of joint cartilage and underlying bone (2).
The most common symptoms are joint pain and stiffness. Other symptoms may include joint swelling, decreased range of motion and when the back is affected weakness or numbness of the arms and legs. The most commonly involved joints are those near the ends of the fingers, at the base of the thumb, neck, lower back, knees and hips (3).
Why Life On Joint-Life Advanced supplement?
Life On Joint-Life Advanced Formulation supplement is a perfect fusion of nutrients which has several benefits than any other existing products in market. It is carefully formulated keeping in mind with most essential ingredients like Hyaluronic Acid, Glucosamine, Chondroitin, Collagen, and MSM, they have been used in various forms for OA for more than a decade and have recently acquired substantial popularity because of their safety and these remedies would have great utility in the treatment of OA.
Glucosamine Sulphate and Chondroitin Sulphate help in repairing the cartilage extracellular matrix. It Increases proteoglycan synthesis by formation of chondrocytes. Chondroitin Sulphate inhibit the activity of degradative enzymes. Implies "anti-osteoarthritic" helps in reducing osteoarthritis of knee and hip joints (4).
MSM helps with mitigation of DA symptoms and decreases joint degeneration and cartilage deterioration (5).
MSM supports in building healthy connective tissues like tendons, ligaments and muscles. It decreases the pressure inside the cell by removing toxins. Taurine is a sulphur containing amino acid formed from methionine. Taurine stabilises cell membranes. Methionine contains sulphur, detoxifies cells and is involved in pain relief (6).
Hyaluronic acid helps in the growth and development of joint's cartilage and bone by promoting the growth of new cells and tissues. Hyaluronic acid plays an important role in reducing joint inflammation and pain caused by injury or tissue degeneration (7).
Collagen hydrolysate supplements are rich in a number of amino acids (a group of chemical compounds) that play an important role in the creation of collagen. Type II collagen is one of the main proteins in cartilage. It's been suggested that taking collagen hydrolysate can improve the symptoms of osteoarthritis by stimulating your body's production of joint collagen (8).
Collagen is an essential protein that provides structure to numerous body tissues. As a person ages, their body produces less collagen. This decline in collagen levels can adversely affect the skin, joints, and connective tissues (9).
References
1. http://www.art:cartilage disorders,nlm.nih.gov/medlineplus/cartilagedisorders.html
2. http://www.art:Atlas of Osteoarthritis, Springer. 2015. p. 21.ISBN 9781910315163. "Osteoarthritis"
3. National Institute of Arthritis and Musculoskeletal and Skin Diseases. April 2015. Retneved 13 May 2015.
4. The Efficacy Of Glucosamine And Chondroitin Sulfate In The Treatment Of Osteoarthritis: Are These Saccharides Drugs Or Nutraceuticals?, Biomedical Papers, 2005 (Vol. 149), Issue 1
5. Glucosamine and Chondroitin Sulfate and Osteoarthritis Food Advisory Committee: Petition Summaries.
6. Methylsulfonylmethane Sulfur (MSM) holistic health journal article MSM.
7. European Union Register on Nutritional and Health Claims.
8. https://www.versusarthritis.org/about-arthritis/complementary-andatternative-treatments/types-of-complementarytreatmen1s/collagerl#:~:1extCollagen%20is%20a%20nutritional%2Osupplement,treating%20osteoarthritis%20give%20mixed%20results.
9. https://www.medicalnewstoday.com/articles/collagen foods#summary